| Round | Opponent | Venue | Date | Home / Away | Result |
| 1 | Richmond | MCG | Sunday 1 April | Home | Win by 17 points |
| 2 | Geelong | Telstra Dome | Saturday 7th April (N) | Away | Lost by 78 points |
| 3 | Essendon | MCG | Saturday 14th April | Home | Win by 3 points |
| 4 | West Coast | Subiaco | Sunday 22nd April | Away | Lost by 61 points |
| 5 | Brisbane Lions | Telstra Dome | Saturday 12th April (N) | Home | Lost by 12 points |
| 6 | St Kilda | Telstra Dome | Friday 4 May (N) | Away | Lost by 43 points |
| 7 | Collingwood | MCG | Saturday 12 May | Away | Lost by 24 points |
| 8 | Kangaroos | Gold Coast Stadium | Saturday 19 May (N) | Away | Lost by 17 points |
| 9 | Adelaide | Telstra Dome | Saturday 26 May | Home | Lost by 19 points |
| 10 | Western Bulldogs | MCG | Sunday 3 June | Home | Won by 10 points |
| 11 | Port Power | Telstra Dome | Saturday 9 June (N) | Home | Won by 39 points |
| 12 | Hawthorn | Telstra Dome | Friday 15 June (N) | Home | Lost by 100 points |
| 13 | Fremantle | Subiaco | Saturday 30 June | Away | Lost by 77 points |
| 14 | Melbourne | MCG | Sunday 8 July | Home | Lost by 23 points |
| 15 | Sydney Swans | SCG | Sunday 15 July | Away | Lost by 62 points |
| 16 | Brisbane Lions | Gabba | Sunday 22nd July | Away | Lost by 117 points |
| 17 | St Kilda | Telstra Dome | Saturday 28th July | Home | Lost by 10 points |
| 18 | Collingwood | MCG | Saturday 4th August | Home | Lost by 24 points |
| 19 | Port Power | AAMI Stadium | Saturday 11th August | Away | Lost by 23 points |
| 20 | Essendon | MCG | Saturday 18th August | Away | Lost by 10 points |
| 21 | Kangaroos | Telstra Dome | Saturday 25th August | Home | Lost by 82 points |
| 22 | Melbourne | MCG | Sunday 2 September (T) | Away | Lost by 31 points |
(Cached)